Oxidative Stress in Aging Human Skin
نویسندگان
چکیده
منابع مشابه
Oxidative Stress in Aging Human Skin
Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging and even more for extrinsic aging. Although the results are quite different in dermis and epidermis, extrinsic aging is driven to a large extent by oxidative stress caused by UV irradiation. In this review the overall effects of oxidative stress are discussed as well as the sources of ROS includin...
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Skin aging occurs through two main pathways, intrinsic and extrinsic. These pathways have significant interaction in contributing to the aging phenotype, which includes skin laxity, wrinkling, pigmentation irregularities, and the appearance of neoplastic skin lesions. Here, we review the critical role that oxidative stress plays in skin aging, including its effects on signaling pathways involve...
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Everyone desires healthy and beautiful-looking skin. However, as we age, our skin becomes old due to physiological changes. Reactive oxygen species (ROS) is an important pathogenic factor involved in human aging. Human skin is exposed to ROS generated from both extrinsic sources such as as ultraviolet (UV) light from the sun, and intrinsic sources such as endogenous oxidative metabolism. ROS-me...
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Constant formation of free radicals mainly reactive oxygen species (ROS) is the main characteristic of all living systems which use oxygen for their basal metabolism. Primarily, ROS are considered an integral component of basic cell regulation and signaling pathways certainly, suppressing tumor progression which forms the basis of the most chemotherapeutic and radiotherapeutic agents. The most ...
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Reactive oxygen species (ROS) is an important pathogenic factor involved in human aging. Human skin is a primary target of oxidative stress from ROS generated from both extrinsic and intrinsic sources, like ultraviolet irradiation (UV) and endogenous oxidative metabolism. Oxidative stress causes the alterations of collagen-rich extracellular matrix (ECM), the hallmark of skin connective tissue ...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2015
ISSN: 2218-273X
DOI: 10.3390/biom5020545